Ubat
Kencing manis sebabkan kanser 5
Reports have
indicated that several Type-2 diabetes therapy drugs increase the likelihood of
pancreatic cancer 25 fold. Of the five drugs that the U.S. Food and Drug
Administration tagged, two are Januvia by Merck & Co. and Byetta by
Bristol-Myers Squibb.
The
drugs, Byetta and Januvia, are in a class of drugs called incretin
mimetics. How incretin mimetics work that when taken, the
drugs make the pancreas increase insulin levels which helps regulate the body’s
blood sugar levels. Now, several studies have been released connecting
these incretin mimetic drug to increased risk of pancreatitis and pancreatic
cancer.
Byetta is
an injectable GLP-1 receptor agonist. The Institute for Safe Medication Practices
(ISMP) released a
report that indicated “injectable medications were . . . 28 times
likelier to be linked to pancreatitis.” However, Merck & Co. and
Bristol-Myers Squibb have both “denied an association between the drug and
pancreatic cancer.”
In
the report, there were 1,723 “domestic, serious” cases recorded in a single
year. Of the total, there were 831 cases of pancreatitis and 105 cases of
pancreatic cancer. Pancreatitis
increases the risk of pancreatic cancer.
Januvia
is a DDP-4
inhibitor taken orally. In independent
studies, Januvia was also
linked to acute pancreatitis, increasing risk of pancreatic cancer.
It wasn’t until earlier this year, when the FDA actually started
investigating, that the risk factors associated with taking Byetta
and Januvia came to light. Januvia hit the market seven years ago, in 2006. Januvia was a veritable
blockbuster drug, reaching tens of billions in sales in just five years on the
market.
“With
millions of people living with Type-2 diabetes across the globe, many are
exposing themselves to these deadly cancers by taking these drugs,” said Christopher
Paulos, attorney with Levin, Papantonio, Thomas, Mitchell, Rafferty
& Proctor P.A. “These drugs provide no additional benefit
above and beyond other, better tested, well-known diabetes therapies.”
Tiada ulasan:
Catat Ulasan
Nota: Hanya ahli blog ini sahaja yang boleh mencatat ulasan.