PATAWALI

Patawali

Brotowali (Tinospora crispa L. Miers) is a herbaceous plant climbers. The height can reach 2.5 m. Prickly stems of this plant resemble soft pseudo pimple. Leaf single-stemmed, heart-shaped or somewhat rounded and pointy toes. Plants are thought to have come from Southeast Asia are commonly grows wild in the woods or fields. With good properties, many people planted in the yard as a medicinal plant. This plant likes hot air places.

High Blood Pressure with Brotowali

Brotowali columbine contain bitter substances, some alkaloids and glukosid, pikroretin amorphous substances, and berberine. Two other alkaloids namely tinosporine and tinosporidine, soft resin, starch, glycosides pikroretosid, Harsha, berberine, palmatin, kolumbin (root), kokulin (pikrotoksin), and pikroretin contained in the leaves.

Blood Pressure Drugs

Part used as medicine are the roots and leaves. The roots taste more bitter and acid, useful as an antipyretic (fever) and diuretic (urine peluruh). Brotowali often combined with other herbs that people used to treat rheumatic fever, yellow fever, diabetes, and as foreign drugs such as scabies, sores, and itching (for bathing). In some countries brotowali also commonly used as medicine. Among them in Sabah, Malaysia, the people there use brotowali to treat high blood pressure, diabetes, diarrhea, and back pain. In Thailand is used as a drug fever, cholera, fitness, rheumatism, intestinal worms and venomous snake bites. In Vietnam is used as a malaria drug. How to use it is, boiled stems or plant parts that are still fresh 30 g or 25 g of the dry in 3 cups water for 20 minutes. Chill and drink ½ cup twice daily before meals. For wounds, boiling water brotowali rod is used to wash wounds such as sores, scabies and others.Pregnant and lactating women are prohibited from taking brotowali. Long-term use can cause liver and kidney damage.

Patawali

Nama Tempatan:	Patawali
Nama Saintifik:	Tinospora crispa(miers)
Nama Lain:	Akar seruntun, brotowali,batang wali
Famili:	Menispermaceae
Lokasi dijumpai:	Dipagar-pagar lama, rumah tinggal
Asal:
keterangan:
Ianya adalah sejenis pokok menjalar yang mempunyai batang berkerutu dan berdaun lebar. Ianya banyak terdapat menjalar dipagar-pagar dan dikawasan rumah lama yang agak terbiar.Seluruh tumbuhan ini mempunyai rasa yang amat pahit sekali dan selalunya disapu pada payudara untuk memudahkan bayi bercerai susu.Batangnya yang pahit itu mempunyai kandungan air yang tinggi. Tumbuhan ini biasa dijadikan bahan yang dicampur dalam minyak urut oleh tukang urut tradisional.Bunganya berwarna hijau muda yang mempunyai 6 mahkota yang berupa tunas.Bunganya kemudian akan berubah merna menjadi merah dan putih apabila matang. Buahnya pula berwarna merah muda.kulit batangnya mengandungi alkaloid dan damar manakala akarnya mengandungi berberin dan kolumbin.
kegunaan:
untuk perubatan, batangnya yang berkerutu adalah bahagian utama yang mengandungi khasiat.Batang Patawali digunakan untuk merawat sakit perut, demam, tekanan darah tinngi, kencing manis dan juga penyakit kelamin dikenali sebagai gonorea.Tumbuhan ini mujarab bagi mengatasi masalah cacing dikalangan kanak-kanak dengan cara merebus batangnya, ditapis dan diminum segelas sehari. Air rebusan juga boleh digunakan untuk membersihkan darah, dan mujarab untuk membunuh kuman dan menyembuhkan luka. Kajian saintifik yang dijalankan ke atas Patawali menunjukkan tumbuhan itu mengandungi sejenis bahan yang dipanggil jattrorrhizine yang dikatakan mujarab untuk menjauhkan penyakit demam malaria.Selain daripada itu ia juga dapat menurunkan tekanan darah tinggi dan meningkatkan selera makan.Pikroretin yang terdapat didalamnya dapat menurunkan suhu panas badan(mengubat demam).Malah diFilipina tonik ini digunakan untuk mengubat sakit jiwa atau tekanan mental.Air rebusan ini juga dapat mengubat sakit pinggang dan sengal-sengal(boleh dicampur dalam minyak urut).Air rebusan ini juga boleh digunakan untuk membasuh kudis-kudis setelah dicampur dengan sedikit belerang.Daunnya digunakan untuk mengubat penyakit sifilis.

upm

The antioxidant and anti-proliferative activity of the aqueous crude extract of Tinospora crispa stem was investigated. The proximate composition of its stem and leaves was determined. Proximate analysis revealed that T. crispa contains - protein: leaves = 4.7%, stem = 1.2%; fat: leaves = 1.5%, stem = 0.43%; carbohydrate: leaves = 11.8%, stem = 19.4%; ash: leaves = 2.7%, stem = 1.1%; moisture: leaves = 79.3%, stem = 77.9%; fibre: leaves = 1.59%, stem = 0.65%; and energy: leaves = 1.59%, stem = 0.65%. The antioxidant activity of the extract prepared at various temperatures and incubation time was evaluated to determine the optimum extraction procedure. Based on DPPH and TBA tests, the preparation of the extract at 60oC for 6 hours was established as the best possible method as it demonstrated the highest inhibition percentage. The extract was tested against brine shrimp to evaluate its toxicity and no significant toxicity was recorded since the IC50 value was more than 1000 μg/ml. The extract produced moderate anti-proliferative activity on selected human cancer cell lines (IC50 MCF-7: 107 μg/ml, HeLa: 165 μg/ml, Caov-3: 100 μg/ml, and HepG2: 165 μg/ml). The findings from this study suggest that T. crispa has the potential to be a source of natural antioxidants and nutrients, besides having a moderate anti-proliferative effect on selected human cancer cell lines.