Khamis, 23 Februari 2012
KHASIAT TONGKAT ALI
A recent research conducted at the Institut Pertanian Bogor (IPB) shows that the Pasak bumi roots plants (Eurycoma longifolia) or in Malaysia known as Tongkat Ali has properties to protect the liver from damage. So far, the public generations believe the earth as a potion pegs to increase male sexual arousal. In addition, the Pasak bumi roots also being used as a tonic for mothers who had just given birth, treatment swollen glands, fever, and dysentery. Pasak bumi roots plants (Eurycoma longifolia) or Tongkat Ali prevent liver damage. But now the benefit of Pasak bumi roots has been proved by Ruqiah Ganda Putri Panjaitan, student S3 Biology Study Program Graduate School IPB in her research titled “Testing Hepatoprotektor Activity of Pasak Bumi Roots. In this research, potion of extracts Pasak Bumi root was tested its effectiveness to the liver function in animals mice. “The results of scientific research shows the pasak bumi roots efficacious in dysfunction sex, anti malarial, and cytotoxic (cell poisoning). While research wedge effect of the earth to protect the liver from damage not a lot done, “said Ruqiah. In his research, Ruqiah spent 12.5 kilograms of dried Pasak Bumi roots, crushed into powder and extracted with methanol solution of 50 percent. Then, repeatedly partitioned with n-heksan, concentrated by vacuum rotavapor. The results of this partition is still through the process of several stages again, until the extract obtained as expected.
Extracts of plants native to Indonesia was then tested on male Sprague Dawley rats aged 2-3 months. Previously, all rats were given doses of carbon tetrachloride with 0.1; 1.0 and 10.0 milliliters per kilogram. Carbon tetrachloride is toxic to the heart of this and lead to necrosis (damaged cells) mice. Animal experiment was divided into three groups, each group consists of three tails. The first group, rats were given distilled water. The second group, mice that were given “Silybum marianum”. Third Group, mice given the extract of the Pasak Bumi or Tongkat Ali roots of the earth peg. Treatment of this mouse lasted for three months. Pasak Bumi root extracts on providing dose 500 milligrams per kilogram of body weight did not result in changes in enzyme levels liver, ie the enzyme “aspartate transaminase, the enzyme” Alanine Aminotransferaz “, and” Alkalenfosfataz “, total protein, total bilirubin, the director and indurek. This picture shows the whole liver cells remain unchanged. Methanol fraction dose peg root water earth and then increased to 1000 milliliters per kilogram of body weight. At this dose, the Pasak bumi root extract showed hepatoprotektor activity. This marked aspartate transaminase enzyme levels and Alanine Aminotransferaz still within the normal range. In addition, images histopathology (tissue exposed to the disease) was comparable to the provision of silymarin. At this dose, the Pasak bumi root extract showed hepatoprotektor activity. This marked aspartate transaminase enzyme levels and Alanine Aminotransferaz still within the normal range. In addition, images histopathology (tissue exposed to the disease) was comparable to the provision of silymarin.