Bromelain

Bromelain paling banyak terdapat pada batang nenas berbanding buahnya. Dipercayai zat bromelain bersifat proteolitik iaitu ia mencernakan protein. Sifat ini sama dengan enzim yang dikeluarkan oleh pancreas iaitu mencernakan protein. Enzim daripada pancreas bersifat alkali.
Enzim yang mencerna protein dipercayai boleh mencernakan protein sel kanser. Justeru pesakit barah disarankan selalu meminum jus nenas. Jus nenas yang ditinkan tidak berapa elok kerana mengandungi pengawet, penstabil, pewarna dan berbagai kimia lagi. Oleh itu, segala enzim semulajadi telah musnah dan anda hanya ditipu oleh label yang menarik pada pembalut botol. Oleh yang demikian, untuk mendapatkan zat yang terbaik, anda perlu rajin membuat sendiri jus anda dengan menggunakan juicer! Jus dari sumber tumbuh-tumbuhan tidak semestinya didapati dari buah sahaja. Jus tumbuh tumbuhan boleh juga dibuat sedari daun! Contohnya, ambil 3 helai daun manggis hijau, 3  helai durian belanda dan sehelai daun jambu dan kisar dengan pengisar biasa serta sedikit air. Tapis airnya dan anda boleh terus meminumnya akan memberi anda vitamin serta kesan zat yang serupa. Yang penting ia perlu dari sumber hijau. Untuk pastikan daun pilihan anda tidak beracun pastikan ia berasal dari daun yang disukai ulat ! Umpamanya daun betik, daun pegaga, daun belimbing, daun mengkudu dsbnya.

Jangan masak jus ini kerana akan merosakkan enzim dan vitamin di dalamnya! Untuk kesan pengubatan terbaik, jus perlu dimakan mentah dan bebas dari racun, kimia pengawet, perisa, pewarna, penstabil, pengemulsi dsbnya !!!

Bromelain is a water extract from pineapple stem that contains cysteine proteinases that have several purported therapeutic effects, including antimetastatic, antithrombotic, anti-edematous, fibrolytic, and immunomodulatory actions.

Efficacy

In vitro and in vivo studies have shown that bromelain inhibits metastasis, stimulate both innate and adaptive aspects of immune function in macrophages and natural killer cells, reduced inflammatory cytokine release in rats injected intraperitoneally with lipopolysaccharide, and inhibited growth of lung tumors in mice inoculated with tumor cells.

Ex vivo human clinical trials of bromelain have shown that oral doses of bromelain (3000 IF.I.P. units) in breast cancer patients for ten days enhanced monocyte cytotoxicity against breast cancer cell lines.

Bromelain in doses of 3000 mg have been found useful in preventing postsurgical adhesions and is used, often in combination with other plant enzymes in the treatment of lymphedema.

Safety

Doses are often expressed in terms of milk clotting units (MCU) or F.I. P. or sometimes in simple milligram weights. Adult safe oral doses range from 400- 4000 mg/day.

Recommendations

Bromelain is routinely used in naturopathic oncology to prevent post-radiation fibrosis and to reduce risk of lymphedema. This practice is based on a small number of clinical studies in post-traumatic and postsurgical edema using Phlogenzym™ a German-manufactured combination enzyme formula containing bromelain

Use of bromelain in prevention of post-radiotherapy fibrosis is supported by a Ukranian paper reporting on the use of bromelain in preventing lympho granulomatosis in cancer patients receiving radiation therapy.

Because bromelain has been shown to be generally safe in oral doses, integrative oncologists often use it for a variety of cancer-related conditions including post-radiotherapy fibrosis, post-surgical edema ileus, lymphedema, immunomodulation, and inflammatory bowel disorders.

 http://depts.washington.edu/integonc/clinicians/act/bromelain.shtml